Transferred Cold Atmospheric Plasma Treatment on Melanoma Skin Cancer Cells with/without Catalase Enzyme In Vitro

Cold atmospheric plasma (CAP) is a promising tool to overcome certain cancerous and precancerous conditions in dermatology. A scheme of transferred CAP was first developed treat melanoma (B16F10) skin cancer cells as well non-malignant (L929) vitro. using silicone tube with jet system that assessed whether it could generate reactive oxygen nitrogen species (RONS) at near-room temperature. The characterized electrically spectroscopically. Biological data showed the killed but not cells. Plasma treatment effective time duration 30 s, whereas were less damaged during treatment. In addition, catalase (CAT) enzyme applied neutralize detoxify RONS generated by CAP. These findings suggest can be considered therapy.